Luca Issi

Q: What is Luca Issi's success rate?

Luca Issi currently has a success rate of 92.74980892038138.

Q: What is the average return of Luca Issi's calls?

Their stock ratings have generated an average return of 30.854874535314323.

RBC Capital | Healthcare

Luca Issi is an analyst from RBC Capital specializing in the Healthcare sector. Ranked #581 out of 4570 analysts, they have issued 44 stock ratings with a success rate of 92.75% and an average return of 30.85%.

Luca Issi has a well-established track record, with 44 ratings issued in the Healthcare sector. They have consistently delivered a success rate of 92.75% and an average return of 30.85%, underscoring their expertise and ability to identify winning opportunities for investors.

#581

Out of 4570

Total Ratings

+92.75%

Success Rate

+30.85%

Average Return

Recent Ratings Analysis

QURE

Buy

Mar 09, 2026

Target

$35.00

Current

$17.99

Performance

0.00%

Luca Issi rated QURE as Outperform on Mar 09, 2026, setting a price target of 35. Shares have remained stable near 17.99, leaving the 35 target still in play.

NTLA

Hold

Mar 03, 2026

Target

$15.00

Current

$13.89

Performance

2.06%

On Mar 03, 2026, NTLA was given a Sector Perform rating by Luca Issi, with a target price of 15. Market indecision, reflected in sideways trading near 13.89, supported the cautious call.

ASND

Buy

Mar 03, 2026

Target

$275.00

Current

$239.92

Performance

0.29%

ASND received a Outperform rating from Luca Issi on Mar 03, 2026, aiming for 275. Price action was muted, as shares hovered around 239.92 despite the bullish outlook.

ARGX

Buy

Feb 27, 2026

Target

$925.00

Current

$740.40

Performance

-3.46%

On Feb 27, 2026, Luca Issi published a Outperform outlook on ARGX, with a target of 925. So far, the stock has neither confirmed nor rejected the Buy case, holding within range of 740.4.

BEAM

Hold

Feb 25, 2026

Target

$26.00

Current

$27.62

Performance

-6.72%

Luca Issi on Feb 25, 2026 assigned BEAM a Sector Perform rating, with a price target of 26. The call successfully avoided chasing as shares lost 6.72%.

MRNA

Hold

Feb 17, 2026

Target

$30.00

Current

$55.74

Performance

26.88%

On Feb 17, 2026, Luca Issi reaffirmed MRNA with a Sector Perform rating, targeting 30. Market strength beyond 55.74 went further than the conservative outlook suggested.

ALNY

Buy

Jan 20, 2026

Target

$465.00

Current

$323.59

Performance

-8.98%

ALNY was rated Outperform by Luca Issi on Jan 20, 2026, with a price objective of 465. This case shows how bullish projections can fail, with the stock now below 323.59.

IONS

Buy

Dec 17, 2025

Target

$95.00

Current

$75.36

Performance

-2.23%

On Dec 17, 2025, Luca Issi initiated coverage on IONS with a Outperform rating and target of 95. Neutral price movement of -2.23% leaves room for interpretation.

ARWR

Buy

Dec 11, 2025

Target

$80.00

Current

$60.67

Performance

-14.33%

Luca Issi issued a Outperform recommendation for ARWR on Dec 11, 2025, price target set at 80. The market hasn’t rewarded the bullish outlook, exposing uncertainty in the call.

WVE

Buy

Dec 09, 2025

Target

$27.00

Current

$13.29

Performance

-37.63%

On Dec 09, 2025, WVE was evaluated by Luca Issi, who gave a Outperform rating and target of 27. Investors saw limited payoff as shares fell short of the 27 target.

FULC

Hold

Dec 08, 2025

Target

$10.00

Current

$7.94

Performance

-38.88%

Luca Issi rated FULC as Sector Perform on Dec 08, 2025, setting a price target of 10. The cautious Hold call aligned with subsequent weakness, as shares slipped 38.88%.

AGIO

Hold

Nov 20, 2025

Target

$28.00

Current

$28.53

Performance

16.12%

On Nov 20, 2025, AGIO was given a Sector Perform rating by Luca Issi, with a target price of 28. The stock rallied from 28.53 to 28.53 after the Hold rating, surprising to the upside.

KRRO

Hold

Nov 13, 2025

Target

$8.00

Current

$12.30

Performance

89.23%

KRRO received a Sector Perform rating from Luca Issi on Nov 13, 2025, aiming for 8. Investors saw gains of 89.23% that the cautious stance didn’t fully capture.

CRSP

Hold

Nov 11, 2025

Target

$50.00

Current

$58.78

Performance

6.47%

On Nov 11, 2025, Luca Issi published a Sector Perform outlook on CRSP, with a target of 50. The Hold call missed some of the bullish momentum as shares advanced toward 50.

RGNX

Buy

Nov 07, 2025

Target

$19.00

Current

$10.38

Performance

-7.40%

Luca Issi on Nov 07, 2025 assigned RGNX a Outperform rating, with a price target of 19. The call has struggled to gain traction, with shares losing 7.40%.

DYN

Buy

Nov 06, 2025

Target

$30.00

Current

$17.69

Performance

-2.80%

On Nov 06, 2025, Luca Issi reaffirmed DYN with a Outperform rating, targeting 30. Market indecision has kept the 30 target in a holding pattern.

RNA

Hold

Oct 28, 2025

Target

$72.00

Current

$14.79

Performance

-78.85%

RNA was rated Sector Perform by Luca Issi on Oct 28, 2025, with a price objective of 72. Investors who stayed cautious avoided some of the 78.85% decline.

LXEO

Buy

Mar 25, 2025

Target

$20.00

Current

$7.44

Performance

67.57%

On Mar 25, 2025, Luca Issi initiated coverage on LXEO with a Outperform rating and target of 20. The stock’s climb of 67.57% since the call highlights the foresight in the rating.

OCUL

Buy

Mar 18, 2025

Target

$17.00

Current

$9.94

Performance

33.42%

Luca Issi issued a Outperform recommendation for OCUL on Mar 18, 2025, price target set at 17. Investors following the Buy call captured upside momentum, with shares now at 9.94.

SGMO

Hold

Mar 18, 2025

Target

$2.00

Current

$0.41

Performance

-51.52%

On Mar 18, 2025, SGMO was evaluated by Luca Issi, who gave a Sector Perform rating and target of 2. The Hold call avoided chasing into subsequent weakness of 51.52%.

MGTX

Buy

Mar 17, 2025

Target

$13.00

Current

$7.37

Performance

-6.35%

Luca Issi rated MGTX as Outperform on Mar 17, 2025, setting a price target of 13. The stock has underperformed, dropping 6.35% despite the bullish target of 13.

ALLO

Buy

Mar 14, 2025

Target

$10.00

Current

$2.50

Performance

28.87%

On Mar 14, 2025, ALLO was given a Outperform rating by Luca Issi, with a target price of 10. The stock rallied 28.87% after the rating, narrowing the gap to the target of 10 and validating the bullish stance.

VERV

Buy

Mar 04, 2025

Target

$15.00

Current

$11.13

Performance

81.86%

VERV received a Outperform rating from Luca Issi on Mar 04, 2025, aiming for 15. Momentum has favored the Buy call, with shares climbing from 11.13 to 11.13, rewarding those who trusted the recommendation.

FDMT

Buy

Mar 03, 2025

Target

$35.00

Current

$8.73

Performance

110.87%

On Mar 03, 2025, Luca Issi published a Outperform outlook on FDMT, with a target of 35. Shares gained 110.87%, underscoring the accuracy of the bullish outlook toward 35.

APLS

Hold

Mar 03, 2025

Target

$25.00

Current

$19.99

Performance

-16.92%

Luca Issi on Mar 03, 2025 assigned APLS a Sector Perform rating, with a price target of 25. The call successfully avoided chasing as shares lost 16.92%.

BMRN

Hold

Feb 20, 2025

Target

$70.00

Current

$60.88

Performance

-11.42%

On Feb 20, 2025, Luca Issi reaffirmed BMRN with a Sector Perform rating, targeting 70. The Hold stance reflected market caution that was later justified.

SLB

Buy

Jan 21, 2025

Target

$57.00

Current

$47.19

Performance

7.89%

SLB was rated Outperform by Luca Issi on Jan 21, 2025, with a price objective of 57. A bullish response from the market helped close the gap of 9.81 to the target.

EDIT

Hold

Dec 13, 2024

Target

$4.00

Current

$2.32

Performance

61.11%

On Dec 13, 2024, Luca Issi initiated coverage on EDIT with a Sector Perform rating and target of 4. The Hold stance underestimated the stock’s strength as it gained 61.11%.

BLUE

Hold

Nov 15, 2024

Target

$80.00

Current

$4.97

Performance

-22.59%

Luca Issi issued a Sector Perform recommendation for BLUE on Nov 15, 2024, price target set at 80. Market action validated the conservative Hold outlook with shares at 4.97.

RARE

Buy

Sep 26, 2024

Target

$77.00

Current

$22.61

Performance

-59.05%

On Sep 26, 2024, RARE was evaluated by Luca Issi, who gave a Outperform rating and target of 77. Investors saw limited payoff as shares fell short of the 77 target.

Frequency Asked Questions

Who is Luca Issi?

Luca Issi is an analyst from RBC Capital specializing in the Healthcare sector.

What is Luca Issi's success rate?

Luca Issi currently has a success rate of +92.75%.

How many ratings has Luca Issi issued?

Luca Issi has issued 44 stock ratings so far.

What is the average return of Luca Issi's calls?

Their stock ratings have generated an average return of +30.85%.

What is Luca Issi's ranking?

Luca Issi is ranked #581 out of 4570 analysts.

What types of ratings does Luca Issi give?

Their ratings include Buy, Hold, and Sell recommendations, depending on the stock’s outlook.

How can I follow Luca Issi?

You can follow Luca Issi by clicking the "Follow Analyst" button on this page to receive updates on their stock calls.

What is the most recent rating by Luca Issi?

Their latest rating was a Buy on QURE issued on 2026-03-09.